Explanation
Yes. The water droplets in a cloud can collectively weigh more than a million pounds. A cloud's fluffy appearance does not mean that its contents have no mass.
NOAA explains that clouds consist of tiny water droplets, ice particles, or both. In a Weather.com explanation, meteorologist Sara Tonks describes an illustrative cumulus-cloud estimate of about 1.1 million pounds of water.
That number is an example, not a standard weight for every cloud. The result depends on the cloud's volume and water content, and the droplets are dispersed throughout the air rather than packed into one solid mass.
Key takeaway
Clouds can contain an enormous mass of water spread across an enormous volume. Their weight varies with size and composition.